What is an AAS?

Following my most recent post on YK11 here, there was discussion about what kind of PED it is... it has the molecular structure of a steroid, is referred to as a steroidal SARM, yet doesn’t seem to be classified as an AAS by vendors or in journals alike.

A quick overview is in order of what a steroid is, and what sets an AAS apart from other steroids. So for folks who didn’t go past 8th grade biology like yours truly, read on.

Defining a Steroid

Steroid: A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.That is, 4 fused rings of carbon atoms, 3 that are six-sided, and 1 that is five-sided. This is what a steroid might look like(demonstrated by the letters ‘A’, ‘B’, ‘C’ & ‘D’).

Steroids have two principal biological functions: as important components of cell membranes which alter membrane fluidity; and as signaling molecules.

Cholesterol is an example of a steroid, as is estrogen and testosterone. Vitamin D is an example of a modified steroid, or secosteroid. There are literally hundreds of steroids, and can be found in plants, animals and fungi. And in /u/nattyfuckface bathroom cabinet.

Defining an Anabolic Steroid

An anabolic steroid (anabolic-androgenic steroid, AAS) has the steroid molecule configuration listed above, while also being (as the name suggests) anabolic and androgenic.

Anabolic: one of two metabolic processes (the other being catabolic, though anabolism is powered by some catabolism). Refers to growth, specifically maintaining and/or increasing muscle mass.

Androgenic: development of masculine features or traits, but can also refer to acne, anger etc. Also known as virilization in the context of women using AAS.

Determining if a Steroid is an AAS

In the 1950s a protocol was created for determining how anabolic and androgenetic a steroid is. Generally speaking, if the steroid has measurable anabolic and androgenetic effects, it is classified as an AAS.

The protocol for determining how anabolic and androgenetic a steroid is uses the relative weights of the ventral prostate and levator ani muscle of male rats. The change in weight of the prostate measures androgenic effects, while weight of the levator ani indicates the anabolism. The ratio of the two weight gains, after being standardized, gives us the anabolic:androgenetic ratio.

Fair warning to this post - AAS are classified as being probably carcinogenic to humans. A carcinogen is anything capable of causing cancer.

So What?

This concludes some basic biology, that may be old news to some, but only vaguely understood by others.

As for YK11 and its status as an AAS… YK11 has anabolic effects, but since it doesn't impact the prostate I could see how it could be argued to not be an AAS by the protocol outlined above. But this is more a deficiency of the determination method: YK11 clearly has androgenic sides speaking from experience. Imo, it is an AAS.