GW0742: Cardarine Sans Cancer (maybe?)


THC is prohibited by the World Anti-Doping Authority, making it prohibited in all major sporting competitions. This seems precautionary or because it is in many places a scheduled drug, as very few studies have tested its ergogenic (performance enhancing) ability, and what we do have shows no direct benefit.

Study 1: Resting heart rate and blood pressure was elevated compared to placebo. No decrease in grip strength, but at high heart rates work capacity declined by 25%.

Study 2: Slight but significant decrease in cycling time to exhaustion after just a single cigarette containing 1.7% of THC

Study 3: During submax exercise (50% of VO2 for 15mins), 7.5mg of THC did not affect blood pressure or O2 uptake, but did affect resting heart rate and recovery.

Study 4: subjects were given 215ug/kg orally which significantly decreased performance, steadiness, reaction time etc.

These studies demonstrate no direct benefit to THC use as it relates to exercise, and a slight performance impairment. But how about indirect or less immediate benefit? For example, after getting high the following days workout session always seems more productive than normal. The key here might be its effect on stress, anxiety and depression. As we covered last week in evaluating caffiene & theanine as a PWO, stress has a negative impact to performance.

For example, a WSU research team found that one puff of cannabis high in CBD and low in THC was optimal for reducing symptoms of depression, two puffs of any type of cannabis was sufficient to reduce symptoms of anxiety, while 10 or more puffs of cannabis high in CBD and high in THC produced the largest reductions in stress.

As stress tends to be cumulative, this could be one area of evaluation. To do so, chronic (heh) use of THC and its impact on exercise would need to be measured. Data which currently does not exist.

So what?

Based on the data so far, THC use is not directly ergogenic and it will impair function and strength. The effect of regular use might have on exercise is unknown, but I can see a theoretical role for its use in stress reduction on non-work out days.

https://www.reddit.com/r/PEDsR/comments/c88i55/performance_enhancing_benefits_of_thc/