T3: stimulates epidermal proliferation, thickening, and hair growth

By /u/MezDez

I found this study interesting.

I personally know that MPB due to DHT isn't direct consequence of DHT but due to an downstream inflammatory response which leads to hair thinning and subsequent loss in follicle density. It appears to be augmented when DHT is in presence of Estradiol. http://www.fitmisc.net/forum/showthread.php?56312-hair-regrowth-protocol

This protocol was created by Taeian Clark who happens to be a Nutrition expert and also a surgeon. Taeian Clark also created the movement of using nandrolone only cycles (he prescribes 2 grams of deca per week) and hundreds of his clients have reported back with zero side effects. Which makes sense given my previous post on Nandrolone only cycles.

Anyways that was somewhat off topic.. But according to this study:


  • The skin is a classic target tissue for thyroid hormone action. Although the histology of skin in hypothyroid states is well documented, the literature contains little assessment of skin in thyrotoxic states. In light of the paucity of information on skin under the influence of excess thyroid hormone, we investigated the direct effect of thyroid hormone on skin.
  • . There was a dose-dependent increase in epidermal proliferation, dermal thickening, and hair growth in T3-treated animals. Mice that received 3.8 microg of T3 had 42% more hairs per millimeter than controls (p < 0.01), hair length that was 1,180% longer (p < 0.001), 49% greater epidermal 3H-thymidine incorporation (p < 0.01), and 80% more 5-bromo-2'-deoxyuridine (BrdU) stained cells (p < 0.05).
  • Thus, topically applied thyroid hormone has dramatic effects on both skin and hair growth. These observations offer a new strategy for developing thyroid hormone and its analogues for treating disorders of skin and hair growth.

I cant access the full article through my university for some reason. But food for thought. I wonder if this applies to MPB induced by inflammation/DHT

btw, the 3.8mcg used in the Mice translates to approximately 57mcg for a 90kilo individual - Which is within what is considered normal (upper end of normal, i think we naturally only produce 30mcg per day)