B6 & Caber Effective in Reducing Prolactin, With Costs
Prolactin is a protein that enables milk production. In men, that’s generally regarded as a bad thing. The only upside is that it might save you from running to the store when you are out and need some for your coffee. There is a form of gyno that originates with high prolactin levels. Within the world of PEDs, high prolactin levels generally come about from the use/abuse of tren… or a pituitary tumor. Vitamin B6 and Cabergoline are generally used to control prolactin, but both have their risks and should be used in their minimum effective dose.
Cabergoline is a dopamine receptor agonist. It makes you feel good. It makes you horny. It can also give you compulsive urges to gamble. It’s incredibly effective at reducing prolactin at low doses, with a 2009 study showing declines of ~90% in prolactin at the first check in, 2.5 months after starting the drug, and 97% reduction in prolactin levels by month 12. In this study at least (sample size of 10) there were no reported side effects at any dose.
The bad news is that side effects are certainly possible as determined by the drug manufacturer/FDA, and include raising blood pressure, irregular breathing, and there is a potential conflict with blood pressure medications, Haldol, Thorazine, and a bunch of others. Given the prevalence of high blood pressure while on cycle, taking anything that may worsen that condition is obviously of concern.
B6 is your other option for reducing prolactin. It is a pretty important nutrient, and serves as a coenzyme in ~100 reactions in amino acids, glucose and lipid metabolism. Fortunately, it’s pretty common in foods that you and I are likely to consume according to the USDA – pork, turkey, beef, bananas, chickpeas, potatoes and some nuts.
At the levels that you want to run it for the anti-prolactin benefits, you will need to supplement. In ye old study, conducted way back in the dark ages of 1982, 600mg was given to a subject group and it kept prolactin steady between 3-4ng/ml throughout the test at around baseline levels, while the control group reported prolactin between 6.1-23ng/ml. Interestingly, B6 also boosted GH significantly.
Short term use of B6 at higher than RDA is ‘possibly safe’, but long-term use of high doses is ‘possibly unsafe’, as it may cause brain and nerve problems (thanks WebMD for this vague information). NIH info is more useful: taking high levels of vitamin B6 from supplements for a year or longer can cause severe nerve damage, leading people to lose control of their bodily movements. The symptoms usually stop when they stop taking the supplements. Other symptoms of too much vitamin B6 include painful, unsightly skin patches, extreme sensitivity to sunlight, nausea, and heartburn. RDI listed by NIH is 1.3mg.
So cycle B6 in conjunction with your prolactin inducing compound. And just like tren, you will cycle off for a time, right? Right?! I know you would. But seriously, don’t run high levels of B6 for longer than a normal cycle. In conclusion, both useful compounds, and both effective at what they do – reduce prolactin. Both have long term side effects, so cycle that shit in conjunction with your PEDs.