HCGenerate: Why I Think It Is (Mostly) Bunk

Taken from the description on Amazon.com:

HCGenerate is an innovative, stand-alone, natural testosterone booster made by Need To Build Muscle. Every man knows and loves the prospects of higher testosterone; Intensity in the gym, superior muscle gains, lower body fat, and most of all, the libido boost. HCGenerate is sold exclusively online and has a customer base that other testosterone products would kill for. What separates HCGenerate from the rest is its unrivaled effectiveness and it’s unique formula that boasts Fadogia Agrestis as its primary testosterone enhancer. Fadogia is known for stimulating testosterone in the male body and doing so quickly. Tongkat Ali and Stinging Nettle are also featured and have long been used as potent male enhancers. HCGenerate is not just a few ingredients, it’s a formula, and with other heavy hitters such as Bulgarian Tribulus, Zinc, and Fenugreek nothing should be stopping you from letting HCGenerate reach all of your goals.

Let’s break these ingredients down, see if there’s anything to this commonly pedaled test booster.

  1. Fadogia has a good amount of literature showing positive effects in mice on increasing the frequency of sex (mounting) and serum testosterone. By Day 5, mice had an increase in serum testosterone of 4x at 100mg/kg body weight. The equivalent dose works out to be ~3225mg for a human (100mg/kg / 6.2 = 16.12mg/kg. For an enhanced male at 200 pounds, the equivalent dose is 16.12mg/kg x 200 pounds). Examine.com takes a more conservative estimate of 700-1450mg. HCGenerate has 1000mg per serving, so I’m going to rank this ingredient as likely to cause an increase in LH based on the research I have read… at least in mice. Edit: /u/NattyFuckFace took a minute to stop building snowmen and shared that: The alterations brought about by the aqueous extract of Fadogia agrestis stem are indications of adverse effects on the male rat testicular function and this may adversely affect the functional capacities of the testes. Ouch.
  2. Tongkat Ali seems to increase testosterone available in a saliva test, which is not an ideal way to measure, but did show almost double the ng/ml when compared to placebo. That said it doesn’t seem to work by increasing testosterone production, but instead stimulates the release of free testosterone, improving the amount of testosterone moving about the body . Still a good thing, but not quite living up to the promise of boosting testosterone, or ‘stimulating testosterone in the male body’, as the product claims.
  3. Stinging Nettle does not have any reliable or verifiable evidence of increasing testosterone in humans. Sorry.
  4. Bulgarian Tribulus. – it has absolutely no impact on testosterone or strength: https://www.ncbi.nlm.nih.gov/pubmed/10997957; https://www.ncbi.nlm.nih.gov/pubmed/11601567; https://www.ncbi.nlm.nih.gov/pubmed/15994038; https://www.ncbi.nlm.nih.gov/pubmed/17530942. Sorry, not sorry.
  5. Zinc. For those with adequate levels of zinc already, zinc (or specifically ZMA, which is Zinc, Magnesium and B6) has no measurable impacts on levels of testosterone production. In this study, researchers took 14 men who were active and aged between 22-33. They also had a baseline zinc intake of 11.9mg – 23.2mg day. The RDA for zinc is 12mg, so what we’re seeing is that subjects were consuming enough zinc prior to the study. During the study, subjects consumed an additional 30mg of zinc, in addition to 450mg of magnesium and 10.5mg of B6.
  6. Fenugreek - In 2009, a study involving 45 resistance trained males were involved in a double blind study with capsules of 500mg of placebo or fenugreek extract. They participated in a supervised 4 day per week resistance training program for 8 weeks. There was no change in free testosterone, estrogen, insulin, cortisol or leptin.

Out of the 6 ingredients found in HCGenerate, the only one that could help boost testosterone is Fadogia.

A 30 day supply of HCGenerate on Amazon.com is $77.99, or $2.60 per dose. A 60 day supply of Fadogia Agrestis on Amazon.com is $22.95, or $0.38 per dose. For this reason, I don’t recommend HCGenerate, and don’t believe that shills pushing the product are trustworthy – it is over priced and has a single effective ingredient that can be purchased much cheaper elsewhere (and that might be bad for your testicles). And in my opinion, that’s exactly what HCGenerate is – one ingredient with a bunch of filler ingredients to pad out the ingredients list and help justify to the consumer the higher price. If you do choose to use a test booster, and research indicates that it is not necessary with testosterone returning to baseline after a SARM only cycle (AAS cycle, different story, do a PCT or b&c) then look at the compounds that you think will help you the most individually, rather than as a packed and hyped product such as this one.